1. Physical and chemical factors

Headache is caused by factors such as inflammation, injury, or tumor compression, traction, stretching, and displacement of pain-causing tissues inside and outside the skull.

(1) Headache caused by compression, traction, stretching or displacement of blood vessels

Common in: 1. Intracranial space-occupying lesions: such as tumors, abscesses, hematomas, etc. that cause blood vessels to rupture Compressed, pulled, stretched or displaced. 2. Increased intracranial pressure: such as hydrocephalus, cerebral edema, venous sinus thrombosis, brain tumor or neurocysticercosis. 3. Intracranial hypotension: For example, after lumbar puncture or spinal anesthesia or surgery or trauma, cerebrospinal fluid is lost more, resulting in intracranial hypotension.

(2) Headaches caused by dilation of intracranial and external arteries due to various reasons

For example, in acute intracranial or extracranial infections, pathogenic toxins can cause arterial dilation; metabolic diseases such as Hypoglycemia, hypercapnia and hypoxia; toxic diseases such as carbon monoxide poisoning, alcoholism, etc.; brain trauma, epilepsy, acute sudden hypertension (pheochromocytoma, nephritis" target="_blank">acute nephritis etc.).

(3) Chemical stimulation of the meninges

1. Bacterial meningitis such as Neisseria meningitidis, Streptococcus pneumoniae, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Campylobacter, Neisseria gonorrhoeae, Bacillus aerogenes, Bacillus pneumonia, Mycobacterium tuberculosis, Brucella, etc.

2. Meningitis" target="_blank">Viral meningitis such as intestinal meningitis. Daovirus, herpesvirus, arbovirus, mumps virus.