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The earliest extant ancient Tibetan medicine works are
The earliest extant ancient Tibetan medical book is Betty Wong Yaozhen.

Betty Wong Yaozhen is a classic of Tibetan medicine written in the middle of the 8th century, which is regarded as the oldest Tibetan medicine classic. This book systematically summarizes the medical experience and treatment wisdom accumulated by the Tibetan people in the long-term struggle, covering a wide range of contents, including drugs, disease diagnosis and treatment methods.