/kloc-at the end of 0/9, two physiologists found that cutting off the dog's pancreas would make the dog get diabetes, which proved that the pancreas contains a substance that can maintain normal blood sugar concentration. 1920 Canadian surgeon Wan Jin read an article saying that pancreatic duct ligation can make pancreatic enzyme-secreting cells shrink, but islet cells are not affected. This article greatly inspired Wan Jin. After bold attempts and painstaking research, Wanjin successfully extracted a valuable pancreatic extract-insulin from the pancreas of dogs for research, and Wanjin won the Nobel Prize for this contribution. From 65438 to 0922, insulin has been used in clinic. 1926, the purified insulin has crystallized. From 1945 to 1955, after 10 years of unremitting efforts, Sanger in Britain finally figured out all the chemical structures of insulin, which laid the foundation for the artificial synthesis of insulin and the study of the relationship between the molecular structure and function of insulin. Sanger also won the Nobel Prize for this contribution.

The discovery of insulin is an important discovery in the field of biomedicine in the 20th century, which has far-reaching significance for saving millions of diabetic patients.