Alexander Hamilton was a politician and military leader in American history. He played an important role in the American Revolution and the formulation of the Constitution. He was also the first Secretary of the Treasury and one of the primary drafters of the U.S. Constitution.

The musical "Hamilton" is based on Hamilton's life and tells the story of Hamilton's growth, political career and death through pop music and hip-hop music. The following is the relationship between the main characters in the musical:

1. Alexander Hamilton: the protagonist of the musical, an important politician and military leader during the American Revolutionary War, and the first Secretary of the Treasury of the United States .

2. Eliza Hamilton: Hamilton's wife, her marriage to Hamilton lasted for 50 years until Hamilton's death.

3. Angelica Hamilton: Hamilton's sister, the link between Hamilton and his wife. She was also Hamilton's friend and ally.

4. Aaron Burr: Hamilton's political opponent, who eventually killed Hamilton in a duel.

5. Thomas Jefferson: The third president of the United States, active on the political stage at the same time as Hamilton and Burr.

6. Margaret "Peggy" Schuyler: Hamilton's friend and ally, and the mother of Hamilton's son Philip.

7. Philip Hamilton: Hamilton's son is a talented actor and speaker in musicals.

The relationships between these characters are revealed in the musical through song and dialogue, forming a complex and rich story.