The infection rate of HBV in China is about 60%-70%. The carrier rate of HBsAg accounts for about 7. 18% of the total population. Based on this calculation, there are about 93 million hepatitis B virus carriers in China, including about 20 million chronic hepatitis B patients. This is an infectious disease, not a genetic disease. There is a safe hepatitis B virus vaccine, drugs are also developing, and new drugs for treatment are also being introduced, and more and more cases will be cured.
Hepatitis B virus (HBV) is one of the smallest DNA viruses known to infect people, with a diameter of only 40,000 times that of human hair, and it is also one of the most difficult viruses to cure. HBV replication has several main characteristics: 1. Although HBV is a double-stranded DNA virus, like HIV as an RNA virus, there is a reverse transcription process in its replication process, which makes the virus genome integrated into the body. On the one hand, it is difficult for the body to completely eliminate the virus, on the other hand, it becomes a potential cancer hazard. 2.HBV can be transformed into cccDNA after entering hepatocytes, and it is hidden in the nucleus for a long time, which is difficult to be completely eliminated even with antiviral treatment; However, once the patient's immunity is low due to long-term use of immunosuppressants or radiotherapy and chemotherapy, cccDNA will jump out to do evil and turn into active replication, which will make HBV infection exist for a long time. Therefore, under the current medical level, HBV is a virus that can be controlled but cannot be completely eliminated.