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What is the significance of self-assembly of biomolecules?
Protein, cells and even life are formed through self-assembly. The self-organization process of the system is essentially a reflection of the order of micro-molecular movement, and it is the result of hundreds of millions of molecules spontaneously "organizing" from disorder and acting in concert. Just as millions of residents in a big city can do the same gymnastics at the same time, it is incredible. This shows that it seems that hundreds of millions of molecules have been instructed or hinted, and they are exchanging information and have a unified sense of time, so as to "keep pace" and act in concert, so that the concentration of some components increases in a specific time and space domain, forming a macro-orderly structure. This self-organization can be said to be the result of a new coherence and intermolecular "communication" mechanism. In the past, people thought that this form of communication seemed to be a convention in the biological world, but now it has also been realized in the chemical system of nonliving substances, which can not but make people feel great surprise and interest, so that they think it is probably a precursor of life or an adaptive mechanism of "pre-organisms". Therefore, Eigen M, the founder of hypercycle theory, believes that there is a molecular self-organization process or a molecular self-organization evolution stage between the chemical evolution stage and the biological evolution stage in the process of the origin and development of life.

All systems in the material world, from elementary particles, atoms and molecules to microorganisms, animals, plants, human beings and human society, whether living or non-living systems, have self-organizing identity in the process of evolution from low to high. This is another evidence of the material unity of the world.

Molecular self-assembly is a common phenomenon in life system and one of the most essential contents of life science. It is of great significance to carry out the research on molecular self-assembly, which will help people understand the process of life formation and evolution in nature at the molecular level and provide new ideas for people to carry out basic biomedical research, synthesize new materials and develop molecular devices.