What does ozone do?
Ozone disinfection technology and its application
Advantages of ozone disinfection
Disinfection has no dead angle, high sterilization efficiency and odor removal. During disinfection, the ozone generator produces a certain amount of ozone, which spreads evenly in a relatively closed environment and has good permeability, which overcomes the problem of disinfection dead angle in ultraviolet disinfection and achieves the purpose of all-round, rapid and efficient disinfection and sterilization. In addition, because of its broad bactericidal spectrum, it can not only kill bacteria propagules, spores, viruses, fungi, protozoa and other microorganisms, but also kill Botox, toxins and rickettsia, and also has a strong role in removing mold, fishy smell and peculiar smell.
No residue and no pollution. Ozone is produced by using oxygen in the air. In the process of disinfection and oxidation, the excess oxygen atoms combine to form molecular oxygen after 30 minutes, and there is no residual substance, which solves the problem of residual secondary pollution in the disinfection process of disinfectant and saves washing again after disinfection.
disinfect
Ozone is a strong oxidant, its molecules are extremely unstable, and it can decompose to produce monoatomic oxygen and hydroxyl groups with strong oxidizing ability. It is a unique bacteriolytic preparation, which can quickly blend into the cell wall, destroy the internal structure of bacteria, viruses and other microorganisms, and has a strong killing effect on various pathogenic microorganisms. The sterilization process belongs to biochemical oxidation reaction. Its function is mainly realized in the following three forms: ozone can oxidize the enzymes needed to decompose glucose in bacteria, so that bacteria are inactivated and die; Nuclear substances act on bacterial cells, such as purine and pyrimidine in nucleic acid, destroying their organelles, DNA and RNA, destroying bacterial metabolism and leading to bacterial death; Ozone has a double chain reaction with bacterial cell wall lipids, which passes through cell membrane tissue and enters cells, acting on outer membrane lipoproteins and inner lipopolysaccharides, causing bacterial permeability distortion and dissolution death; Ozone acts on four polypeptide chains of virus capsid protein, damaging RNA and destroying its protein. After the bacteriophage is oxidized by ozone, its epidermis is broken into many fragments, from which many ribonucleic acids are released, which interferes with its adsorption of sediments.
The function of ozone mainly focuses on five aspects: anti-inflammation, anti-infection, analgesia, cholesterol oxidation, immunity improvement and oxygen supply to ischemic tissues. However, because the molecular structure of ozone is a special molecule composed of three oxygen atoms, although it has strong oxidation, it is also very unstable. Under normal temperature and pressure, it will be automatically reduced to oxygen after 20 minutes. So at present, the ozone used in clinic is self-made, and it is usually made by ozone generator. Its formation principle can be obtained by high voltage discharge, corona discharge, electrochemistry, photochemistry, atomic radiation and other methods. The principle is that a part of oxygen in the air is decomposed and polymerized into ozone by high-voltage electricity or chemical reaction, which is a process of oxygen allotrope transformation. After being made into ozone, it can be dissolved in sterile water, blood, body fluids or directly act on tissues as needed to achieve different therapeutic purposes.
clinical application
The clinical application of ozone has developed from the initial treatment of colitis and skin gangrene to today's treatment of stroke, rheumatic diseases, joint diseases, disc herniation, anti-free radicals and anti-aging, chronic wounds caused by acute and chronic hepatitis, prostatitis and pressure ulcers, vaginitis and so on. However, the treatment effect, operation technology and popularization and application are mainly reflected in the following aspects:
Treating intervertebral disc herniation
The most widely used and mature technology in clinic is the treatment of cervical and lumbar disc herniation. At present, percutaneous laser vaporization decompression combined with ozone interventional therapy is generally used. Under local anesthesia, curved needle technique was used. During laser vaporization, the position of the needle tip is constantly adjusted until the ideal position, and the laser fiber is placed. After vaporizing twice, ozone with a certain concentration was injected into the intervertebral disc and paravertebral space with a syringe to achieve the effect of diminishing inflammation and relieving pain. This method is not easy to relapse after treatment and has no side effects on patients. At present, it is a new technology adopted by hospitals. [7]
Treat viral liver disease
Ozone is also effective in treating acute and chronic viral hepatitis. Patients with viral hepatitis have edema, degeneration and other inflammatory reactions due to virus invasion into liver cells. Ozone is a strong oxidant, which can quickly denature the virus RNA and stop the metabolism of bacteria, thus playing an anti-inflammatory role.
Because ozone can also enhance human immunity, induce the production of cytokines and protect the liver, ozone is used to treat viral hepatitis. The research data also show that ozone therapy can quickly reduce transaminase, reduce yellowing, reduce virus level and inhibit virus replication in patients, and it is a new treatment method without toxic side effects. In 2000, ozone treatment of viral hepatitis was approved for clinical use in Europe, and in 2004, this technology was approved for clinical use in China.
Treating ischemic and hypoxic diseases
Tylicki et al. reported 12 hemodialysis patients with arteriosclerosis and lower extremity arterial thrombosis were treated with high pressure ozone for 9 times respectively. Results The average total cholesterol decreased by 8.34%, the average low density lipoprotein decreased by 17.9%, and the activity of the eighth factor had no obvious change, indicating that this method had no damage to the vascular endothelial system of patients, while the total cholesterol and low density lipoprotein decreased. [7]
At home, ozone has been used to treat gynecological infections, such as candida vaginitis; It has also been reported that ozone water washing combined with microwave is used to treat chronic cervicitis, ozone self-blood therapy is used to treat patients with bronchial asthma and has achieved good results, and ozone is used to treat wound healing caused by burns, and the effect is very remarkable. [7]
Ozone has been used in clinic for less than 50 years, but it has shown its advantages in many aspects and is gradually replacing some traditional treatment methods. From 65438 to 0999, Italy initiated and established the International Medical Ozone Association, the main purpose of which was to promote the basic research and clinical application of ozone and provide clinical treatment standards.
At present, the Association is working with medical workers to find new methods and new directions of ozone in clinical application, such as multi-channel puncture, combination of ozone technology and collagenase technology, and double needle technology in the treatment of lumbar disc herniation. It is believed that more and better new ozone technologies will be applied to clinic soon, bringing good news to more and more patients. From this perspective, the development prospect of ozone should be very broad. However, ozone also has contraindications in clinical application.
First of all, ozone can not be directly inhaled into the lungs, because direct inhalation will cause the destruction of alveolar epithelial cells; Secondly, patients with silkworm bean disease cannot be treated with ozone blood therapy; Third, ozone therapy will cause very few allergic reactions; Fourth, when ozone therapy is carried out, excessive concentration and dose will cause poisoning reaction.
Prevention and control of vegetable diseases
Using ozone to control vegetable diseases has been studied abroad for a long time, and there have been related reports in China in recent years. Using the ozone with low mass fraction generated by the ozone controller of greenhouse plant diseases, all airborne diseases and most soil-borne diseases of fruits and vegetables such as cucumber, green pepper and eggplant can be prevented and controlled. Low mass ozone can effectively prevent cucumber downy mildew, powdery mildew, anthracnose, stem blight and mosaic virus from occurring in a large area, and can also prevent eggplant and kidney bean gray mold. Ozone not only has obvious control effect on diseases, but also has control effect on some pests, for example, the control rate of aphids is 63% ~ 68%.
Removing pesticide residues from vegetables
When eating vegetables, the most worrying thing is pesticide residues. Although agricultural administrative departments have formulated many methods to reduce pesticide residues, emphasizing the rational use of pesticides and advocating the use of biological pesticides and pesticides with high efficiency, low toxicity and low residue, pesticide poisoning incidents in vegetables still occur from time to time. Traditional methods for removing pesticide residues include soaking and washing, soaking in alkaline water, peeling, storage and heating. Dr. Pan Canping of China Agricultural University pointed out that it is difficult to remove pesticide residues in fruits and vegetables by traditional water immersion method, and high concentration ozone immersion can effectively remove pesticide residues. Studies have shown that using ozone to culture bean sprouts can effectively degrade pesticides on bean sprouts. After bean sprouts were soaked in 3mg/L ozone water for 30min and cultured for 8h, the degradation rates of pesticides on them were carbofuran 100%, diazinon 76% and dichlorvos 96%. Chlorothalonil, omethoate, trichlorfon and dichlorvos on vegetables were treated with ozone, and the pesticide residues after treatment reached the international allowable standards.
Vegetable fresh-keeping processing
Cleaning and disinfection of vegetables
Cleaning fruits and vegetables with ozone-containing water can not only effectively kill pathogenic bacteria and spoilage bacteria attached to the surface of vegetables, but also remove other toxic substances remaining on the surface of vegetables. This is one of the methods to maintain and improve the safety of new plant food. Studies show that this method can reduce the total number of bacteria on the surface of fruits and vegetables by more than 90%, especially for Escherichia coli.
Fresh-cut vegetables
Western developed countries began to research and produce fresh-cut vegetables as early as 1950s, and now a complete, advanced and systematic processing system has been formed. With the acceleration of people's life rhythm and the improvement of food safety awareness, fresh-cut vegetables are becoming more and more popular in China. However, at present, most fresh-cut vegetables sold in supermarkets have undergone rough processing such as simple cleaning and cutting, lacking advanced purification processing technology, and consumers still have concerns and doubts about their safety and hygiene. Ozone has a good killing effect on microorganisms on the surface of vegetables, and its oxidation can oxidize the ethylene damage caused by fruits and vegetables, which has an ideal effect on delaying the after-ripening of vegetables and maintaining the fresh quality of vegetables. In recent years, the application of ozone in fresh-cut vegetables has been studied at home and abroad. The research shows that ozone water soaking can not only significantly reduce the microorganisms on the surface of fresh-cut vegetables, improve the safety of products in microorganisms, but also significantly inhibit the degradation of chlorophyll in fresh-cut vegetables, inhibit the activity of polyphenol oxidase and protect vitamin C, but may have a certain oxidation effect on reducing sugar.
Vegetable storage
Vegetables are still living organisms after harvest, and respiration is one of the most important physiological activities after harvest. Inhibition of respiration can prolong the shelf life of vegetables. Many experiments show that ozone can obviously inhibit the respiration of vegetables during storage. Its principle of action is that vegetables are easy to release ethylene during storage, and ozone can oxidize and remove ethylene, thus slowing down the metabolism of fruits and vegetables. In addition, ozone can also destroy the odor of organic or inorganic substances, and has the functions of deodorizing and purifying the air, so it can be used to disinfect the storage environment of vegetables and maintain an environment conducive to maintaining the vitality of vegetables.
Desalination of salted vegetables
Vegetables are easy to eat in the peak season and not in the off-season. People usually make some vegetables into pickles and pickles. For example, pickled mustard tuber, pickled mustard tuber and radish are the main pickles. In the process of salting, 8% ~ 15% or even higher concentration of salt is generally used for salting, which makes the taste too salty to be eaten directly, and even salt poisoning may occur. Therefore, pickles need to be desalted before eating. The traditional desalination method is to soak in tap water. After desalination, microorganisms multiply in large quantities, especially in summer, which is easy to grow films, bloom and become soft. Ozone has the property of killing many kinds of microorganisms. The results showed that the number of microorganisms in pickles soaked in ozone was significantly lower than that in pickles soaked in tap water.
What is ozone for?
Ozone has the following ten effects: 1. Ozone can stimulate the proliferation and phagocytosis of white blood cells in the body; 2. Kill bacteria and viruses. Ozone reacts with body fluids to produce hydrogen peroxide to prevent and kill bacteria and viruses. 3. Reduce the binding force of oxygenated hemoglobin, ozone can activate red blood cells, increase the levels of adenosine triphosphate and 2,3-glycerophosphate, increase the oxygen carried by blood, promote the division of hemoglobin, reduce the binding force of oxygenated hemoglobin, and thus improve the diffusion of oxygen from blood to cells; Ozone has a good auxiliary anti-cancer effect, and the key to cancer is hypoxia at the cell level. With the participation of ozone, the oxygen content in blood increases, and its ability to directly supply oxygen to tissues is enhanced, which improves the hypoxia state of cancer cells, improves their sensitivity to radiotherapy rays, and reduces the occurrence of multidrug resistance in chemotherapy. At the same time, it promotes the production of interferon, IL-II and tumor necrosis factor, and also has a positive effect on tumor prevention and treatment. 5 oxidative degradation of petrochemical products, ozone's super oxidative decomposition ability can also oxidative degradation of petrochemical products, to some extent, to prevent the occurrence of stones; Ozone therapy can improve blood oxygen saturation and blood oxygen partial pressure, increase and disperse the elasticity of red blood cells, change the aggregation mode of platelets and a number of hemorheological indexes, thus improving their ability to pass through capillaries, enhancing their ability to supply oxygen and energy to tissues, activating cell activity and restoring tissue metabolism and function; Adjust the immune system, activate T lymphocytes, increase the release of cytokines such as interferon, interleukin and tumor necrosis factor, and improve the immune function of the body; Regulate the body's antioxidant capacity. Ozone can instantly increase the number of "free radicals" by interacting with the body, induce and activate the antioxidant enzyme system of the body, and produce a large number of free radical scavengers such as superoxide dismutase, thus eliminating excessive free radicals and regulating the antioxidant capacity of the body; Ozone can promote the utilization of sugar, promote the circulation of tricarboxylic acid, increase the release of energy, and restore the basic metabolism to normal state; 10 decomposes wastes and toxic substances produced by metabolism, and ozone can oxidize and decompose wastes and toxic substances produced by human metabolism and promote their excretion; Xie recovered and entered a normal state; 10 decomposes wastes and toxic substances produced by metabolism, and ozone can oxidize and decompose wastes and toxic substances produced by human metabolism and promote their excretion;
The main function of ozone
The function of ozone mainly focuses on five aspects: anti-inflammation, anti-infection, analgesia, cholesterol oxidation, immunity improvement and oxygen supply to ischemic tissues. However, because the molecular structure of ozone is a special molecule composed of three oxygen atoms, although it has strong oxidation, it is also very unstable. Under normal temperature and pressure, it will be automatically reduced to oxygen after 20 minutes.
So at present, the ozone used in clinic is self-made, and it is usually made by ozone generator. Its formation principle can be obtained by high voltage discharge, corona discharge, electrochemistry, photochemistry, atomic radiation and other methods. The principle is that a part of oxygen in the air is decomposed and polymerized into ozone by high-voltage electricity or chemical reaction, which is a process of oxygen allotrope transformation. After being made into ozone, it can be dissolved in sterile water, blood, body fluids or directly act on tissues as needed to achieve different therapeutic purposes.
Extended data:
Ozone destroys microbial membrane structure by oxidizing oxygen atoms to achieve the purpose of sterilization. Ozone can always inactivate bacteria quickly. Different from other fungicides, ozone can react with lipid double bonds in bacterial cell walls, penetrate into bacteria, act on protein and lipopolysaccharide, change cell permeability, and lead to bacterial death.
Ozone also acts on nuclear substances in cells, such as purines and pyrimidines in nucleic acids, to destroy DNA. Ozone first acts on the cell membrane, destroying the components of the membrane and causing metabolic disorder. Ozone constantly penetrates the membrane, destroying lipoproteins and lipopolysaccharides in the membrane, changing the permeability of cells, leading to cell lysis and death.
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The role of ozone
Use of ozone
1. Ozone mainly exists in the ozone layer below the stratosphere 20 kilometers away from the earth's surface, with a content of about 50ppm. It absorbs short-wave ultraviolet rays harmful to human body and prevents them from reaching the earth, thus shielding ultraviolet rays from life on the surface of the earth.
2. Ozone can be used to decolorize wastewater. Chromophoric groups in colored substances include: vinyl, azo, azo oxide, carboxyl, thiocarboxyl, nitro, nitroso and so on. Ozone can open their unsaturated bonds and make them lose their color rendering ability.
Ozone oxidation of phenol in water is a free radical reaction. First initiated by chain, then introduced hydroxyl, and finally oxidized to carbon dioxide and water. Ozone can also oxidize cyanide in electroplating wastewater.
The oxidation of inorganic metal ions such as Fe2+ and Mn2+ by ozone is similar to that of chlorine, which oxidizes them into stable precipitates with higher valence. Ozone and activated carbon are simultaneously used to treat wastewater. Activated carbon can catalyze ozone oxidation and reduce ozone consumption.