Three Renaissance masters, Leonardo da Vinci, Michelangelo and Raphael,14-16th century, can be simply understood as 1500 years, separated by hundreds of years. Because there was baroque rococo in the late Renaissance, then neoclassicism, and then impressionism.
The three pioneers were not sure, because the Renaissance was not only painting, but also destroyed in the dark ages of the Middle Ages. The black history of religion revived after Byzantium and Renaissance, and literature and art revived before ancient Rome and ancient Greece, so it was called Renaissance.