Ma Rui was born in Zhaotong, Yunnan in 1972. He graduated from the Folk Music Department of Shanghai Conservatory of Music and further studied in the Performance Department of Shanghai Theater Academy. He is a film and television actor.

In 2001, she played Shen Juan in "Wu Tong Yu". In 2003, he starred in "First Love" adapted from Sha Liu's novel "Autumn is Like Fire". In 2006, she starred in the TV series "Cangwu Tianshan" directed by Cheng Hao, playing the role of Mary. In December 2010, he played Liu Min in the TV series "The Kindness of Doctors". In June 2014, she played "Hao Jiangyan" in "Wife's Lies". In July, she starred in the emotional legal drama "Golden Lawyer".