Western music is an art type with historical, regional, cultural and other characteristics. It contains profound aesthetic significance and also has important cultural value. The music of the Western Regions integrates many cultural elements such as music, dance, literature, art, religion, etc., and spreads around the world through the Silk Road, changing the musical styles of the East and the West for more than a thousand years, and also driving changes in literary trends and social culture. In the process of its dissemination, development and integration, it has had a profound impact on "Silk Road Culture" and is an important part of the Silk Road Culture landscape. The music of the Western Regions has important literary and artistic theoretical research significance and social and cultural significance in the exchange and integration of Eastern and Western cultures.