"Leizhou Nie Mei" means "cooperative sisters" in Cantonese. Members of the Da Nanshan Cooperative in Leizhou City, Guangdong Province use this name to address their companions. Later, with the spread of network terms, "Leizhou Ni Mei" gradually became popular in the network and became one of the words that netizens called each other.

The popularity of "Leizhou Ni Mei" is also related to the local dialect. There are many local languages in Guangdong Province, and with the popularity of the Internet in recent years, dialect vocabulary in many places has gradually been accepted and used by netizens. In Guangdong, "Leizhou Ni Mei" is widely used. The word was born in the local cooperative. Although it originated in a small place, it has become a widely circulated network term because of mutual communication.

Although the original meaning of "Leizhou Nie Mei" is "cooperative sister", the use of this title on the Internet is more flexible. Some people use it to tease people who are willing to "cooperate", and "Leizhou Ni Mei" has also become a humorous irony. Others use it to express their feelings and show intimacy. No matter where it is used, it has become a part of the network language, making people's speech more colorful.