A. Rogge, published in 185 1, p. 439. Oxley said that Malaysian aborigines used to take Dongge Ali decoction to treat intermittent fever. Malay women also take Dongge Ali decoction as a tonic after delivery.
B. Malay Pharmacopoeia, 1939, written by John Jemlant and H.W. Thomson, described Tengger as: "The infusions and decoctions made from its roots are drunk by Malays as tonics".
The Dictionary of Economic Products of Malay Peninsula written by C.I.H. Bokhel in 1936 describes Dongge Ali in detail: "Roots, especially the bark of roots, are used as antipyretics. Bark is extremely bitter, although it is abundant on the peninsula, but the trade volume is very small, and then it is exported from Borneo to Singapore. This medicine has a good reputation after oral administration, which makes people believe that it is also effective for external use. They mashed the roots and applied them to the affected areas to treat headaches, ulcers, wounds and pains, and even the pain caused by syphilis. "
D. The official Indian Materia Medica, published in 1908, was written by Nadkani and Tenggara Ali. It is described as a small tree growing in Malaysia, and its bark and roots can be used as antipyretic. It is also said in the book that root is the medicine for malaria after quinine.
Traditionally, Malays and other indigenous people in Malaysia regard Tengger singer Ali as an energy tonic, an antipyretic, an aphrodisiac and an antidote to poisoning and snake venom, which is well documented in the literature.
Julius Terry Hadia, director of the Biological Taxonomy Department of Indonesian Botanical Garden, described the tradition of using East Gia in Southeast Asia as follows: "In Southeast Asia, all parts of East Gia trees, especially the roots, have long been used as medicines to treat fever, oral ulcers and intestinal (stomach) worms. Women can be used as tonics after delivery. In Sumatra and Kalimantan, it is an antipyretic; It can treat dysentery in Nanbang and Belidong. "
"In Sabah and Kalimantan, people take the decoction of Tengger Ali bark to relieve the pain of bones, and the decoction of its leaves can be used to scrub the skin to relieve itching. In Vietnam, Dongge Ali Huaguo decoction can cure dysentery. Malays mash branches and leaves for external use to treat headaches, stomachaches, syphilis pains and other pains. The author has done research in this field in RIAU, and people drink the decoction of Tengge Ali to treat malaria. Now, Dongge Ali is more widely known as an aphrodisiac. "
American literature
The essence of TONGKAT ALI has a considerable effect on male muscle growth.
The British Journal of Sports Medicine reported that the effect of tongkat ali (Dongge Ali) essence improved muscle mass by 5% in five weeks. This result was obtained from a double-blind controlled scientific experimental treatment group, and no obvious side effects were found in the control group. An increase of 5% in five weeks is a great progress, and if the effect of one year is added up, the effect will be more obvious (an increase of 5% in five weeks; 52 weeks is 50%). Among these interesting facts, newspapers and magazines pointed out that the patient's arm circumference increased significantly from 30.87( 1.88)cm to 32.67( 1.96)cm, (p=0.0 1 1). We can see the sampling clinical trials of healthy men through the following address of the British Journal of Sports Medicine.
Cytotoxic active components and antimalarial drugs extracted from Pueraria Aridon by the Department of Chemistry of National national cheng kung university, Tainan City, Taiwan Province Province.
Cytotoxicity and antimalarial components from Pantotrichum. )
Based on the comprehensive analysis of 1D and 2D NMR spectra and a large number of spectral data, 65 compounds were isolated from the roots of Ye Guang jujube. Among them, four diterpenoids were found from natural resources for the first time, and they were named Eurycoma lide A (1), Eurycoma lide B (2), 13beta, 2 1- dihydroxy eurycolon(3) and 5alpha respectively. 14β, 15β- trihydroxyquinolinone (4). Through cytotoxicity test, these compounds also have anti-H Ⅳ and anti-malaria effects in vitro. Compounds 12, 13, 17, 18, 36, 38, 59 and 62 have been proved to have strong cytotoxic effects on human lung cancer (A-549) cell chain. However, 12, 13, 17, 38, 57, 58 and 59 have strong cytotoxic effects on human breast cancer (MCF-7) cell chain. Compounds 57 and 58 have strong antimalarial activity against Plasmodium falciparum. This comprehensive stereochemical study of diterpenoids provides a clear reference for scientists interested in this field.
In vitro antimalarial activity of diterpenoids from Pueraria lobata against Plasmodium falciparum in Malaysia
(Plasmodium falciparum)
In vitro antimalarial activity of picrotoxin from Pantotrichum against chloroquine-resistant Plasmodium falciparum isolate in Malaysia. )
Three diterpenoids extracted from the roots of Pueraria lobata have antimalarial activity against nine plasmodium falciparum, which come from patients infected with chloroquine-resistant malaria. The results showed that patchouli alcohol, patchouli alcohol 2-o-β-d- glucopyranoside, 13β, 18- dihydropatchouli alcohol had antimalarial activities, and their IC50 values were 1.23 1-4.899 μ m, respectively. 0.389-3.498 μm and 0.504-2.343 μm, in contrast, the IC50 value of chloroquine is only 0.323-0.774 μm m..
Effect of Ali of Pueraria lobata on Target Sexual Behavior of Middle-aged Male Rats
In this experiment, middle-aged Sprague-Dawley mice raised in Minton, Penang, Malaysia, were fed with different doses of Dongge Ali twice a day for ten days to observe the effects of drugs on their target sexual activities, including their desire to detect their own non-reproductive and reproductive changes, and their restricted and unrestricted activities. The results showed that during the experiment, compared with the experimental control group, the treated subjects increased their activities (sniffing anus and licking), their own reproductive modification and restricted activities in specific areas, but decreased their activities (crawling and eager to detect) in the external environment. Conclusion: This study further proves that different doses of Dongge Ali can improve the target activity of middle-aged male rats.
Dongge Ali can enhance the sexual desire of male rats with sexual experience.
(Long Ye Guang Jujube enhances the sexual desire of male rats with sexual experience. )
Department of Pharmacy, Malaysia University of Science and Technology (Minton, Penang, Malaysia) In this study, male rats with sexual experience were fed with different doses of Tengge Ali of 400 and 800 per kilogram of body weight, respectively. 10 days later, the effect of Tengge Ali on male rats' sexual desire was observed. The results showed that these animals increased the frequency of straddle riding under the action of drugs. After taking 400mg/kg of chloroform, methanol, water and butanol extracts from Dongge Ali, the riding frequency of some male rats was 5.31.2, 4.9 0.7, 4.8 0.7 and 5.2+. However, those who took 800 mg/kg were further increased to 5.4 0.8, 5.4 0.8, 5.2 0.6 and 5.3 0.2 respectively, but no erection, sexual intercourse and ejaculation occurred during the observation period of sexual arousal caused by straddle riding, which was not affected by other behavioral factors. Studies have proved that Tengge Ali is a very effective sexual stimulant for male rats who show strong performance but lack sexual sensory feedback.
Dongge Ali strengthened the sexual motivation of middle-aged male rats.
Department of Pharmacy, Malaysia University of Science (Minton, Penang, Malaysia) This experiment studied the effect of Dongge Ali on sexual motivation of middle-aged male rats and retired mice, using improved open field and runway selection methods. Each mouse took 500mg/kg of four kinds of extracts of Radix Puerariae Ali, namely chloroform, methanol, butanol and water, while the control group and yohimbine group took 3ml/kg of common alkali salt and 30mg/kg of yohimbine (or aphrodisiac) 10 day respectively. The results show that after a period of time, the correct choice that rats can make has risen briefly. 50% middle-aged mice treated with the extracts of Pueraria lobata and Yohimbine can make correct choices within 8 days and 5 days after treatment respectively. This study shows that Ali dongge can continuously enhance the sexual motivation of mature and middle-aged male rats and retired mice.
Breakthrough of phytochemistry and traditional herbal medicine in treating sexual dysfunction
Breakthrough of phytochemicals and traditional herbs in the treatment of sexual dysfunction. )
Department of Pharmacy, Hangdu University, Indonesia, Naval Teaching Hospital: Traditional herbs are a revolutionary breakthrough in treating erectile dysfunction, such as Viagra Dongge Ali, which has become a world-famous plant. Modern views on erectile dysfunction tend to be single-source theory, for example, erectile mechanism. In order to restore erection, oral drugs and vascular injection or penile injection are widely used. Modern phytochemistry is developed from traditional herbs. Phytochemistry advocates treating the root cause, that is, treating the causes of the normal dysfunction of the whole human body. Therefore, phytochemical treatment of erectile dysfunction is carried out under the overall framework of sexual dysfunction. Protodioscin is a phytochemical extracted from Tribulus. Clinical experiments have proved that through the transformation between protodioscin and DHEA(De-Hydro-Epi- androsterone), sexual desire and erection can be improved. Preliminary observation showed that the effective activities of protodioscin extracted from Tribulus terrestris grown in different soils were different. This inconsistency also exists in other herbs, such as various kinds of ginseng, anise, ginkgo, yohimbine and so on. This requires further study on the causes of phytochemistry.
Effect of Long Ye Guang Jujube on Sexual Ability of Middle-aged Male Rats
(Effect of Long Ye Guang Jujube on Sexual Ability of Middle-aged Male Rats)
In this experiment, middle-aged male rats were fed with 0.5g/kg long leaf E.longifolia) 12+02 days, while the other control group was fed with 3ml/kg salt every day to study the effect of long leaf E.longifolia on sexual ability of middle-aged male rats. The experimental results show that Ali Tengge can shorten the preparation time of sexual behavior and enhance the sexual ability of middle-aged male rats. The preparation time of sexual behavior in each group taking the Ali extract of Pueraria lobata was 865-9 16 seconds, which was 9 1-96% of the control group and 860-9 14 seconds (92-98)% of the group B. 850-904 seconds (93-904 seconds), 880 seconds (100%), 855 seconds (100%), 860 seconds (100%) and 800 seconds (100%) in group C. This result continued throughout the experiment. In addition, the response rate of male rats taking 0.5g/kg dongge Ali for a long time to make correct choices after the experiment also increased briefly. More than 50% of male rats can react correctly after two weeks of drug treatment with Dongge Ali, and this effect is particularly obvious during the observation period. However, the sexual ability of middle-aged male rats taking ordinary alkali salt did not increase, and only 45-45% of male rats could react correctly during the experiment. Therefore, this study shows that Ali dongge can improve the sexual ability of middle-aged male rats, which further supports the folk use of Ali dongge as an aphrodisiac.