Suxiao Jiuxin Pill has been used in clinic for more than 20 years. After hundreds of millions of applications, it is famous for its rapid, remarkable and lasting curative effect on angina pectoris of coronary heart disease. In recent 20 years, the long-term application of medical literature reports has achieved good results in improving patients' cardiac function, anti-atherosclerosis, improving microcirculation and protecting myocardial cells. The longest follow-up time I know is 5- 10 years. Results Xiao Su Jiuxin Pill can obviously reduce the incidence of myocardial ischemia and the death caused by cardiovascular diseases. A large number of clinical results also confirmed the efficacy of Xiao Su Jiuxin Pills. Moreover, due to the special way of taking dripping pills-sublingual administration, it has little irritation to the gastrointestinal tract, and there are few reports of adverse reactions in the literature. In recent years, a large number of basic research results have emerged, such as one of them: ligustrazine, the main component of Xiao Su Jiuxin Pill, improves the preservation effect of heart during heart transplantation, and ferulic acid prevents atherosclerosis, which makes the mechanism of Xiao Su Jiuxin Pill more clear.