Trioxide (strong oxidant, oxygen and ozone) is a kind of active oxygen, which consists of three oxygen atoms, so it is called O3. It is a strong oxidant with a half-life of about 20-30 minutes at room temperature, which is easy to decompose and more soluble in water than oxygen. Since Siemens invented the first ozone generator in 1857, it has been used for disease medication and health care, and it has a history of 130 years. During World War I, German soldiers used ozone to treat gas gangrene caused by anaerobic infection. 1972, the first ozone society was established in Germany, which marked the wide application of ozone therapy in clinic. Subsequently, the European medical community continued to report the new progress of ozone treatment of diseases. Professor Bocci from the University of Siena, an Italian scholar, applied ozone to the treatment of lumbar intervertebral disc for the first time according to its anti-inflammatory, analgesic and proteoglycan dissolving effects in nucleus pulposus, and achieved good results. In 1990s, ozone was widely used to treat neck, shoulder, back and leg pain in foreign medical circles, and the total effective rate was about 75% ~ 80%. At present, in Germany, France, Italy, Russia, Portugal, Cuba and other countries, ozone therapy and ozone health care have become a very prosperous industry, and ozone therapy equipment and ozone health care equipment are widely used. At the beginning of 2000, ozone therapy was gradually popularized and applied in China, mainly used for conservative treatment of cervical and lumbar disc herniation, and achieved positive results.

Trioxide ablation can eliminate aseptic inflammation, release soft tissue nodules around vertebral body and treat various soft tissue injury diseases. Trioxide intervertebral disc fusion can quickly dissolve the collagen substance of intervertebral disc herniation and promote the absorption of inflammatory substances. Tongningsongjie liquid has the functions of stopping bleeding, relieving pain and improving microcirculation. Minimally invasive three-knife positioning, eight-character approach and rotary separation combined with water needle knife are safe and effective. Therefore, ozone water needle knife is a minimally invasive technique with remarkable curative effect in the treatment of lumbar disc herniation and soft tissue injury.