1644, people didn't I don't know what bacteria are, although their history is much longer than human history. In the historical records of China, the epidemic situation often represents the epidemic of infectious diseases caused by bacteria. In the late Ming Dynasty, there were many plagues in the north. Plague began to appear in Shanxi province from 1988. There was an epidemic in Shanxi Province every six years, and it reached its peak in ten years, 167. During the thirteen to seventeen years of Chongzhen, there were many epidemics in Henan. Near Beijing, in the thirteenth year of Chongzhen, Shunde and Hejian became popular. In the sixteenth year of Chongzhen, a great epidemic occurred in Tongzhou, Changping and Baoding and was introduced to Beijing. Like Shanxi, in the second year of the first epidemic, that is, in the seventeenth year of Chongzhen, the epidemic in Beijing reached its peak in March and April. What is this epidemic raging in North China? Dead rats in the east and west are the most important infectious diseases in human history: plague. At that time, people didn't know the route of transmission, because every epidemic only knew it was related to the death of mice by watching them die, so they got the name plague. Twenty years later, Japanese Kitasato Shibasaburo and French Yersin isolated a bacterium from plague patients in Hong Kong, which proved that this bacterium was the source of soe-472 plague. People began to understand the plague and found the hand of prevention. However, in 1644, people had to wait for death in the face of the plague. The most famous plague epidemic in history is the Black Death, which wiped out nearly half of the population in Europe in the14th century. The Black Death spread from mouse to mouse through flea bites and from mouse to mouse. It has a rapid onset and a high mortality rate. When I was in Enemy at the Gates, the plague in Beijing happened to be the critical moment of sudden outbreak. Think about the panic situation when the virus was in Beijing a few years ago. If you have enemies, how can you keep them? Plague is popular among the people and soldiers living in a bad environment, and bureaucratic families are rarely affected, so Chongzhen in the deep palace doesn't know, and neither does Li Zicheng outside the city. I don't know. When Li Zicheng wanted to crusade against the besieged city, the soldiers guarding the city put it forward before the siege began. This is because everyone knows that they can't keep it. In this way, Li Zicheng can't-I don't believe he easily entered Beijing. At the same time, neither can he. I don't believe that his dream of a prosperous city has been defeated now.