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Extraction code: ulse title: gene biography (hardcover edition)
Author: [America] Siddhartha Mukherjee
Translator: Ma
Douban score: 8.6
Publishing House: CITIC Publishing House
Publication year: 20 18-4
Page count: 620
Content introduction:
brief Introduction of the content
Throughout the 20th century, there were three subversive scientific concepts and technical applications that brought human society to a new historical stage: the discovery of "atom" brought revolution in physics, the discovery of "byte" brought revolution in Internet and the discovery of "gene" brought revolution in biology.
Gene is not only the basic unit of genetic material, but also the basis of all biological information. When the operating mechanism of genes is solved, the mystery of life will be solved, and human pathology, behavior, personality, disease, race, identity and destiny will be updated. Nowadays, gene sequencing, gene cloning and other genetic technologies have developed rapidly, and the human genome project has also completed the comparison and sequencing of all human genes, and the era of human conquest of genes has arrived.
Gene Biography tells the origin, development and future of gene theory completely, and it is a biography reflecting the history of gene development.
Gene Biography is also a story of scientists overcoming difficulties in the process of exploring the mystery of genes. Like detective stories, it takes the new problems that scientists constantly encounter as clues to deepen step by step, which not only combs the context of gene theory in a simple way, but also truly records the cooperation and struggle, success and failure of scientists. The Biography of Genes also tells the historical disasters and lessons brought about by the political distortion and utilization of gene theory, as well as the collision and game between gene technology and system, culture and ethics. There are wonderful stories, human entanglements and historical advances and retreats. Gene Biography is a common sense book with temperature and superb narrative.
Humans have never been infinitely close to the truth of life like today. When we can control and transform human genes, the concept of "human" may change fundamentally, and the post-human era is coming. The story told in Gene Biography is closely related to everyone.
After its publication, Biography quickly topped Amazon's list, becoming a best seller in The New York Times and a good book of the year in Seattle Times of Washington Post.
In 20 10, Mukherjee's "The King of Diseases: The Biography of Cancer" described in detail the origin and development of cancer and the history of human beings' fight against and prevention of cancer, and won the Pulitzer Prize for literature after its publication, but this book did not reflect the normal life before cancer lesions. If cancer is the devil after human pathological changes, what forces maintained the normal metabolism of the body before that? In the process of cancer research, the author realized that only by understanding the positive and negative aspects of things can we deeply understand its internal mechanism. Therefore, in the process of exploring the mystery of normality and genes, the author created another book that went deeper into the source of human destiny and subverted life cognition-Gene Biography. Cancer is about the morbidness of life, while gene is about the normality of life, so gene transmission can be regarded as the prequel of cancer transmission.
-CITIC Publishing Group? See polis (publisher of genetic biography)
Gene Biography is not only a detailed account of the history of scientific development, but also a declaration of human beings facing the future in the 2/kloc-0 century.
-Ma Xiangtao (translator of Gene Biography)
Knowledge series (produced by knowledge city-state):
Knowledge series 0 1: time chart: great history,1300 million years ago to the present [America] David? kristian
Knowledge series 02: new things in the sun: the global interaction between human beings and the environment in the 20 th century [America] John? Macneil
Knowledge Series 03: Revolutionary Era: 1789- 1848 [English] Eric? Hobsbawm
Knowledge Series 04: Capital Age: 1848- 1875 [English] Eric? Hobsbawm
Knowledge Series 05: Age of Empire: 1875- 19 14 [English] Eric? Hobsbawm
Knowledge Series 06: Extreme Age:1914-1991[English] Eric? Hobsbawm
Knowledge series 07: the bell of the night watchman: the crisis and way out of our time [America] Rebecca? Costa
Knowledge series 08: 19 13, the world before World War I [UK] Charles? Emerson
Knowledge Series 09: History of Civilization: Inheritance and Exchange of Human Civilization for 5,000 Years [France] Fernand? Braudel
Knowledge series 10: gene biography: the source of all beings (paperback+hardcover) [America] Siddhartha? Mukghi
Knowledge series 1 1: the outbreak of ten thousand years: how civilization accelerates human evolution [America] Gregory? Cochrane [America] Henry? Habendin
Knowledge series 12: torture Europe: cooperation, resistance and revenge during world war ii [America] istvan? tool
Knowledge series 13: Columbus communication: biological shock and cultural shock after 1492 [America] Alfred? W. crosby
Knowledge series 14: from dawn to decline: 500 years of western cultural life, 1500 to the present (paperback+hardcover) [America] Jacques? Barzan
Knowledge Series 15: Plague and Man [America] William? Macneil
Knowledge series 16: the rise of the west: the history of human community [America] William? Macneil
Knowledge Series 17: The End of the Ottoman Empire: War, Revolution and the Birth of Modern Middle East, 1908- 1923 [America] Sean? McMeekin
Knowledge Series 18: The Birth of Science: A New History of Scientific Revolution (Volume I) (Paperback+Hardcover) [America] David? Wootton
Knowledge series 19: civil war, a history of ideas [America] David? Armitage
Knowledge Series 20: The Fifth Beginning [America] Robert? L. Kelly
Knowledge series 2 1: A brief history of mankind: from animals to gods (hardcover) [attached] Herari? Yuval
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N reasons for reading Biography of Genes:
1. Not all books about genes can be read by you.
The story told in this book is closely related to everyone who is alive. All your questions about pathology, behavior, personality, disease, race, identity and fate will find new answers in the book.
3. Who are you? Where did it come from? Where are you going? The discovery of genes has finally brought us infinitely close to the real answers to these big questions.
4. This book has written the human exploration of the mystery of life gene iteration for 3000 years.
5. Why is everyone similar but different? In the evolution of life, what determines everything behind it? This problem has puzzled mankind for thousands of years. From Aristotle to Darwin, mankind has been exploring it. It was not until 1950s that scientists discovered genes and finally found the key to the mystery of life.
6. The book tells the story of 240 scientists who overcame many difficulties in the process of exploring the mystery of genes:
A. the discovery process of A.DNA double helix is thrilling and wonderful as a blockbuster.
B Nazi Germany used the theory of "eugenics" to make the concentration camp an eternal scar in the hearts of the world.
C. You think that all scientists should be "I adore you", but in fact, even if they cooperate, they may not forget their struggle.
D an American girl who performed "well" in school was identified as "mentally retarded" with her mother.
E. You think you are a woman, I think I am a man, but the gene says we may all be wrong.
7. Genes have no emotion, and genes have temperature.
8. If you have to find similar works, take yuval harari's A Brief History of Mankind for example. "A Brief History of Mankind" retells the story of mankind from its origin to today with a brand-new historical perspective and superb writing skills. Biography of Genes also tells a thorough story about genes from a grand perspective and concerns about the ultimate problems of mankind with extremely exquisite narrative means.
9. There were many books about genes before, but they were scattered. They have never combed the origin, development and future of gene theory completely and systematically like Mukherjee. Gene Biography is a famous book with high knowledge density.
10. This is not a blunt popular science book. The author also interspersed with political, historical, human nature, ethics, morality and other issues. This is a very thick work.
1 1. Good-looking, really good-looking, one question after another, scientists seize the clues and evidence of fragments, and break through the genetic problems one by one, which looks like a detective novel.
12. This book can give us a complete understanding of all the knowledge of genes. It is enough to read this book about genes.
13. Indian-American doctor, this status makes the author's writing unique.
14. Mukherjee's previous work "The King of Disease: The Biography of Cancer" won the Pulitzer Prize. He is good at telling stories.
15. In the future, this book is about everyone's future! Gene technology has developed rapidly. Gene sequencing, gene cloning, gene detection, gene diagnosis, gene editing ... these technologies can bring us great benefits, cure diseases, predict the future, update our knowledge of gender, identity and choice, and the gene era is coming. However, genes also involve intellectual differences, racial discrimination and ethics. In the 1940s, Nazi Germany distorted the use of gene theory and created a genocide. Human beings have mastered the technology of directional genetic modification, which affects the function of genes, thus changing the physical state, physiological function and even human beings themselves. So who has the right to control them and ensure safety? Who will be the leader of this technology and who will be its victims? When we have the ability to understand and master the human genome, the traditional concept of "human" may change, and the post-human era is coming.
16. Mukherjee is very handsome, huh!
Fundamentally speaking, human beings are just carriers carrying genes and expressing functional pathways. Genes are the source of the growth of all things in nature, and we are passed down from generation to generation like horse racing. Their composition has nothing to do with good and evil in the world. At the same time, it will not be affected by human feelings. We are only the ultimate embodiment of these genetic materials.
-Haruki Murakami 1Q84
Famous recommendation
The New York Times bestseller, 20 16 elite reading list.
Washington Post Book of the Year
The Economist's 20 16 Annual List
MIT Science and Technology Review Editorial Department 20 16 Science and Technology Books Worth Reading.
Bill? Gates (founder of Microsoft)
Hao (founder of children's travel plan, author of Beijing Folding)
Ji (CEO of Shell Network, founder of Scientific Squirrel Society, Ph.D. in Neurobiology)
Kai-Fu Lee (CEO of innovation works, Dean of innovation works Institute of Artificial Intelligence Engineering)
Li Qingchen (Ph.D., popular science writer, author of The Legend Outside My Heart, an award-winning work of Jinwen Book Award)
Liang (Professor and Economist, Beijing Technology and Business University)
Liu Suli (founder and famous scholar of Beijing Wansheng Bookstore)
Wu Guosheng (Head of the Department of History of Science, Tsinghua University)
Yin Ye (CEO of Huada Gene, creator of life science popular science program "Arabian Ye Tan")
Zhang Yu (MD, deputy chief physician, author of Only Doctors Know)
Anthony? Dole (Pulitzer Prize winner, author of All the Lights We Can't See)
Paul. Berg (Nobel Prize winner in chemistry)
Red? Reid hoffman (founder of LinkedIn)
Maria? Maria Ramos (CEO, Bank of Balek, South Africa Branch)
Joint recommendation!
No one is more suitable than him to lead us to understand the past, present and future of genetic science ... At the same time, Mukherjee is an elegant storyteller.
Bill? Gates
There are two things that determine the future destiny of mankind, one is artificial intelligence and the other is genetic technology. With the discovery of genes and the rapid development of gene theory and technology, human beings have the opportunity to approach the truth of life secrets infinitely. Dr. Mukherjee's biography comes at the right time, which completely combs the origin, development and future of gene theory and technology, tells the story of scientists overcoming difficulties, and the touch of gene technology on the boundaries of social ethics and culture. Like his previous work "Biography of Cancer", it is informative and enlightening. We are full of confidence in the future of gene technology. In the coming genetic era, human beings have more possibilities to overcome diseases and control their own destiny, and no longer resign themselves to fate.
-Kai-Fu Lee (CEO of innovation works, Dean of innovation works Artificial Intelligence Engineering Research Institute)
The discovery and development of genes reveal the mystery of life and will profoundly affect the direction of our human society. Mukherjee is an Indian-American. He is a doctor, scholar and popular science writer. On the one hand, he has mastered the scientific knowledge about genes, on the other hand, as a popular science writer, he can present profound knowledge with literary style, with stories and plots, which makes people read heartily.
—— Ji (CEO of Shell Network, founder of Scientific Squirrel Society, Ph.D. in Neurobiology)
I recommend this book not only because it is really good, but also because of its significance. Yuval? In A Brief History of the Future, which is popular all over the world, Herali pointed out that the future development of mankind depends on two major sciences, one is artificial intelligence, and the other is bioengineering. Bioengineering is also called genetic engineering. This science has been used in pharmacy, gene detection and gene recombination. Using genetic science, we can save people's lives and eliminate the defects inherited from our ancestors. Isn't this a better future for mankind? To understand the future of genetic science, we must understand its past and present, which is the significance of reading gene biographies.
—— Liang (Professor and Economist, Beijing Technology and Business University)
The author switches back and forth between ancient reverie, scientific and technological progress and the ups and downs of scientists' personal destiny, showing us a vast and profound historical picture, which is a masterpiece of popular science that can not be ignored in recent years.
-Li Qingchen (Ph.D., popular science writer, author of "Legend Outside the Heart", an award-winning work of Jinwen Book Award)
Mukherjee is a valuable doctor. He can do both research and writing. He makes abstruse medical concepts no longer obscure, and makes non-professionals feel the beauty of genes and genetics. It is hoped that the publication of Biography of Genes will let more people know about gene technology, which is a great deal in the history of modern medicine.
-Zhang Yu (MD, deputy chief physician, author of Only Doctors Know)
Everyone knows that genetic technology is very important to human beings, but most people only see the magical results and can't see the process. Reading this biography of genes is a very interesting process. For example, a winding path leads to a secluded place, where you can not only see the dawn brought by new discoveries, but also see that the dawn is covered by dark dense forests, and finally see the light that breaks through the dense forests again, which makes people feel more excited about scientific exploration.
-Hao (founder of children's travel plan, author of Jing Zhe)
From the first anthropoid ape to the modern man endowed with science and technology, we have never stopped our curiosity about ourselves and our search for the source of our ancestors. Genes are the basis of shaping human beings, but we have known them for less than one hundred years. Biography of Genes describes the development history of genetic science from the perspective of humanistic care, with strong stories and rich emotions, vividly shows the genetic law and discovery process of genes, and inspires human thinking about the future. What really threatens the future security of mankind is not the possibility that technology is out of control, but how people who master technology choose. Kant said two amazing and awe-inspiring things, the starry sky above his head and the moral law in his heart. The endless exploration of science will eventually make the surprise disappear, but I hope the awe of morality will never change.
-Yin Ye (CEO of Huada Gene, creator of popular science life science program "Tian Fang Ye Tan")
This is not a book that only introduces biotechnology and common sense. Its most valuable place lies in reinterpreting the collision and game between technology and system, culture and ethics from the unique perspective of genes and under the macro-framework of human social and historical development.
Elephant association
Although I hate to admit it, for a long time in the past, most doctors in China, especially a large number of grassroots doctors, regarded treating diseases as treating symptoms and having stable vital signs. Understanding genes can help doctors better understand life and expand their career boundaries. Siddhartha, the author of Gene Biography? Dr. Mukherjee, because of his "dual" experience in tumor clinical and research, his writing makes clinicians understand the content of this field from a cordial perspective.
-Lilac Garden
If you like prose, this book is just what you want. If you want to know about gene coding-not as good as a doctor of genetics, but enough to control the whole situation of this topic at the dinner table-then this book is for you. This book can make you think, but at the same time it can also help you avoid the burden of thinking.
-Saura Buha (medical science writer, royal surgeon)
This work may be regarded as a rare thriller detective novel for thousands of years, including Aristotle, Mendel and Francis? Collins and other scholars have contributed to exploring the mysteries of life. As a companion of The King of Diseases: The Biography of Cancer, The Biography of Genes not only inherits the grand narrative style, but also becomes a classic beyond the former. If you expect to know about the present and future of mankind, then this book is an indispensable masterpiece.
Anthony? Dole (Pulitzer Prize winner, author of All the Lights We Can't See)
20 10, Siddhartha? Dr Mukherjee once fascinated readers with his Pulitzer Prize-winning work "The King of Disease: A Biography of Cancer". Now it seems that this is just a warm-up before the official debut of Gene Biography. He turned this book into an epic work integrating science, history and autobiography, which is comparable to the literary masterpiece Paradise Lost in breadth and depth.
-The New York Times
The story has been described in detail in many different ways, but this time, Mukherjee told this new history with a rare grand vision.
-The New York Times Book Review
Mukherjee explained abstract scientific concepts through touching stories ... At the same time, he also showed tenderness, fragility and light in human nature in poetic language under the premise of medical rigor.
-Washington Post
In Mukherjee's romantic narrative context, his eyes sharply point to those contradictory details and unresolved irony. This genius keenly locked in the emotional truth hidden in the chemical abstract, making you seem to have successfully passed a university course that you dare not sign up for, and enjoyed every minute of the process.
Andrew? Solomon (author of The Devil at Noon), Washington Post.
Gene Biography is a history of life science thoughts, connecting the past with the future. The author interprets the scientific problems that are widely concerned at present with meticulous logic.
-USA Today
Gene biography not only depicts the grand blueprint for the development of life science, but also poses a moral and philosophical challenge to the traditional concepts of human beings.
Paul? Berg (Nobel Prize winner in chemistry)
This radical, controversial and friendly book in the modern situation is so wonderful. After reading it, equip yourself to meet the coming of the future.
Brian? Ai Boya (author of How to Live Forever), Sunday Times
His (Mukherjee's) clear and charming description of the historical background is the embodiment of his ambition and the testimony of his indelible achievements. It is worth mentioning that there is no credible and vivid investigation left in his book.
The guardian
This is a masterpiece containing complex thoughts ... Chinese is meticulous, readable and interesting, and it can be said to be one of the important works in all scientific revolutions. It is destined to have a fundamental impact on our next generation.
-"Observer"
Gene biography explores an eternal and complex theme. In fact, it is intertwined with our daily life, and the author makes it closer and more exciting.
Mark? Hayden (author of "The Mysterious Movement of Dogs in the Late Night")
About the author:
Brief introduction of the author
Siddhartha? Siddhartha Mukherjee is an Indian-American doctor, oncologist and well-known popular science writer.
He studied at Oxford University, received his doctorate in medicine from Stanford University and Harvard University, and is an assistant professor at Columbia University Medical Center. His research focuses on cancer treatment and gene function related to blood cells. Published "The King of Diseases: A Biography of Cancer" in 20 10, and won the Pulitzer Prize for Literature the following year. Time magazine called it "one of the influential English books since 1923 100". After the publication of Gene Biography on 20 16, it quickly topped the Amazon list and became a best seller in The New York Times and a good book of the year in Seattle Times of Washington Post.
Brief introduction of translator
Ma, researcher/deputy chief physician, graduated from Peking University with a doctorate in surgery. He has been engaged in clinical and basic research of surgical oncology for a long time, translated monographs such as Gene Biography and Clinical Trial of Cancer, and won the Medal of Outstanding Medical Worker in the Capital. Dr. Ma is the director of Haidian District Medical Resources Co-ordination Service Center, and concurrently serves as the editorial board of Cancer Prevention Research and cancer research and clinic. He has published more than 65,438+000 articles in dozens of domestic and foreign journals such as Chinese Medical Journal, Oncology, Medicine and Philosophy. Dr. Ma is committed to medical humanities exchange and popularization of health knowledge, and now his family lives in Beijing. (WeChat: DRXIANGTAO, welcome to exchange and discuss. )