Green chemistry is a new interdisciplinary subject with clear social needs and scientific goals. Green chemistry has rich connotations and is closely related to biology, physics, computer science, materials science and earth science. The implementation of green chemistry needs the knowledge of the above disciplines as the foundation and drives the development of these disciplines. From a scientific point of view, green chemistry is the renewal and development of traditional chemical thinking mode; From the environmental point of view, it is to eliminate pollution from the source; From an economic point of view, it makes rational use of resources and energy, reduces production costs and meets the requirements of sustainable economic development. Green chemistry, also known as environment-friendly chemistry or environment-friendly chemistry, avoids and eliminates the use of raw materials, catalysts, solvents and reagents, as well as products and by-products, and strives to make chemical reactions "atomic economy" and realize "zero emission" of waste. Therefore, green chemistry is the key to the development of ecological economy and industry, and an important part of sustainable development strategy. The core scientific problems of developing green chemistry are to study new reaction systems, including new synthetic methods and routes, to seek new chemical raw materials, including renewable biomass resources, to explore new reaction conditions, such as supercritical fluid, environmentally friendly media, and to design and develop environmentally friendly products. Green chemistry and environmental management are completely different concepts. Environmental treatment is to treat the polluted environment and restore it to its original appearance, and green chemistry is a new strategy to prevent pollutants from producing at the source, which is called pollution prevention. Since there is no use, generation and discharge of pollutants, there is no problem of environmental pollution. Therefore, only through green chemistry and developing environment-friendly chemistry and green chemistry technology from scientific research can we solve the contradiction between environmental pollution and sustainable economic development. (1) The historical development and present situation of green chemistry is the frontier of international chemical research. 1990, the United States promulgated the Pollution Prevention Act and established it as a national policy, which promoted the rapid rise and development of green chemistry in the United States. 1996 The U.S. government established the "Presidential Green Chemistry Challenge Award" to reward the achievement of using chemical principles to fundamentally reduce chemical pollution. 1997 American national laboratories, universities and enterprises jointly established the Institute of Green Chemistry. The American Chemical Society established the Institute of Green Chemistry. Japan has formulated a "New Sunshine Plan" with green chemistry as its content, such as environmental protection manufacturing technology. Europe and Latin America have also made scientific research plans for green chemistry and technology. The number of international conferences on green chemistry is increasing day by day, which shows the latest research results of green chemistry and is highly valued by academic circles. There is a Gordon conference on the theme of green chemistry in the United States every year. The Gordon Green Chemistry Conference was held in Oxford, England from 65438 to 0999, and the monographic collection Green Chemistry: Theory and Application was published at the same time. In the same year, the Royal Society of Chemistry founded the international chemistry magazine "Green Chemistry", which immediately set off an upsurge of green chemistry in Europe. In a word, green chemistry and technology have become an important research and development direction that governments, enterprises and academic circles all over the world pay attention to. China also attaches great importance to the research of green chemistry, a new discipline. 1995, the Department of Chemistry of China Academy of Sciences determined the "green chemistry and technology-the way to promote the sustainable development of chemical production". 1997 the national natural science foundation and China petrochemical group jointly funded the major basic research project of "environment-friendly petrochemical catalytic chemistry and chemical reaction engineering", and held the international advanced seminar on green chemistry from 1998, which promoted the development of green chemistry in China. It will be held once a year in the future, and the fourth international advanced seminar on green chemistry was held in Shandong Province on 200 1. (2) Prediction of the development of green chemistry As a new interdisciplinary subject, green chemistry has become a hot spot and frontier of current chemical research, and it is an important direction of chemical development in 2 1 century. The main research problems of green chemistry in the next ten years (also known as 12 principle) are: 1) to stop pollution from the source, not to control pollution at the end; 2) the synthesis method should be "atomic economy", that is, all the atoms involved in the process should enter the final product as far as possible; 3) Try not to use or produce substances that are toxic and harmful to human health and the environment in the synthesis method; 4) Design chemicals with high efficiency and low environmental toxicity; 5) Try not to use auxiliary substances such as solvents, and it must be harmless when it has to be used; 6) The production process should be carried out under mild temperature and pressure, and the energy consumption should be the lowest; 7) Try to use renewable raw materials, especially replacing mineral raw materials such as oil and coal with biomass; 8) Minimize by-products; 9) using a highly selective catalyst; 10) chemical products should be degraded into harmless substances after use and can enter the natural ecological cycle; 1 1) Develop timely analytical techniques to monitor the formation of harmful substances; L2) Select substances involved in chemical processes to minimize the risk of accidents.