There are many factors leading to high prothrombin time and prolonged prothrombin time, but the fundamental reason is the lack of coagulation factors. All the reasons leading to the decrease of coagulation factors may lead to the prolongation of prothrombin time. The reason why prothrombin is an important item in liver function examination must reflect some changes in liver function.

The liver is the main place for the formation of coagulation factors. When liver function is damaged, coagulation factors cannot be synthesized normally, which leads to the increase of prothrombin time. When prothrombin time is higher than normal, it will show a series of symptoms such as easy bleeding on the body surface and difficult to stop bleeding after bleeding. Such as gingival hemorrhage and traumatic hemorrhage. At the same time, prothrombin takes a long time, and the body is prone to blue-purple plaques. When the body is slightly compressed, it will produce blue or purple plaques, which will gradually disappear after a few minutes.

In addition to the phenomenon that abnormal liver function leads to the increase of prothrombin, there are also reasons such as congenital coagulation factor deficiency and secondary/primary fibrinolysis.