Most European countries believe in Christianity and Catholicism. Russia mainly believes in the Orthodox Church, so there are also great contradictions between the two sides on religious issues. Therefore, it has also caused great differences in some concepts and living habits between the people of both sides. In addition, conflicts and grievances often broke out between Russia and European countries in history. For example, Napoleon invaded Russia at that time and Hitler invaded the Soviet Union in World War II, so both sides left a very deep grudge.
Of course, nowadays, the society pays attention to global cooperation and development, and the economic development of Europe now relies heavily on Russian energy, because Russia now exports a large amount of natural gas to European countries, which also makes European countries rely heavily on Russian natural gas imports. So the relationship between European countries and Russia is very complicated now, because once the relationship with Russia deteriorates seriously, Russia will cut off the supply of natural gas to European countries.
Moreover, the two sides have great differences on racial issues. Although they are all white-skinned, they are basically different races. Historically, European countries looked down on Russians. But now European countries have to rely on Russian energy to develop their economies.