Why can't humans go into hibernation? Is it because humans lack hibernation genes? In contrast, biologists say that human beings are not short of so-called hibernation genes, and the fundamental reason why animals can hibernate but humans can't hibernate should be the selective expression of genes. Biologists further explained that when animals enter hibernation, the genes responsible for consuming and decomposing fat will be activated, and the genes responsible for regulating carbohydrate activity in the body will stop expressing, thus maintaining the vital signs of the body and enabling the internal organs of the body to work normally without absorbing too much oxygen.
After understanding the hibernation mechanism of hibernating animals, scientists began to imagine whether the expression of genes can be controlled by some external substances, so that the human body can enter hibernation. At the beginning of the experiment, scientists thought of hydrogen sulfide gas. Many people have heard of hydrogen sulfide gas, which is a toxic gas, giving off the smell of rotten eggs and often giving people uncomfortable experiences.
In the experiment, scientists implanted a hydrogen sulfide donor into mice and put them to sleep. In this state, scientists have observed that the vital signs of mice are very stable and can survive for a long time under the condition of very low oxygen concentration. After a while, the pediatrician took out the hydrogen sulfide donor from the mouse, and the mouse began to wake up slowly. When they are fully awake, they will act as before without any discomfort.
Scientists say that hydrogen sulfide is promising as a new hibernation drug. However, it should be noted that when the concentration of hydrogen sulfide reaches a certain level, it will combine with some enzymes in mitochondria, thus blocking the flow of oxygen and easily leaving cells in an anoxic state. So the content of hydrogen sulfide is very important, and too much hydrogen sulfide will lead to death.
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General review of the first volume of the seventh gr